Publications scientifiques 2011

1. Ni W, Le Guiner C, Gernoux G, Penaud-Budloo M, Moullier P, Snyder RO. Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates : implications for gene doping. Gene Ther.2011 Jul ;18(7) :709-18.Epub 2011 Mar 10.

2. Le Guiner C, Moullier P, Arruda VR. Biodistribution and shedding of AAV vectors. Methods Mol Biol. 2011 ;807 :339-59

3. Joussemet B, Belbellaa B, Mendes-Madeira A, Bucher T, Briot-Nivard D, Dubreil L, Colle MA, Cherel Y, Moullier P, Rolling F. Neonatal systemic delivery of scAAV9 in rodents and large animals results in gene transfer to RPE cells in the retina. Exp Eye Res. 2011 oct ;93(4) :491-502.Epub 2011 Jun 24.

4. Léger A, Le Guiner C, Nickerson ML, McGee Im K, Ferry N, Moullier P, Snyder RO, Penaud-Budloo M. Adeno-associated viral vector-mediated transgene expression is independant of DNA methylation in primate liver and skeletal muscle. PLoS One. 2011 ;6(6) :e20881.Epub 2011 Jun 8.

5. Montheilhet V, Saheb S, Boutin S, Leborgne C, Veron P, Montus MF, Moullier P, Benveniste O, Masurier C . A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6 and 8. Mol Ther 2011 Nov ;19(11) :2084-91

6. Galiacy SD, Fournié P, Massoudi D, Ancèle E, Quintyn JC, Erraud A, Raymind-Letron I, Rolling F, Malecaze F. Matrix metalloproteinase 14 overexpression reduces corneal scarring. Gene Ther.2011 May ;18(5) :462-8

7. Stieger K, Cronin T, Bennett J, Rolling F. Adeno-associated virus mediated gene therapy for retinal degenerative diseases. Methods Mol Biol.2011 ;807 :179-218

8. Rouger K, Larcher T, Dubreil L, Deschamps JY, Le Guiner C, Jouvion G, Delorme B, Lieubeau B, Carlus M, Fornasari B, Theret M, Orlando P, Ledevin M, Zuber C, Leroux I, Deleau S, Guigand L, Testault I, Le Rumeur E, Fiszman M, Chérel Y. Systemic delivery of allogenic muscle stem cells induces long-term muscle repair and clinical efficacy in Duchenne muscular dystrophy dogs. Am J Pathol. 2011 Nov ;179(5) :2501-18

9. Martino AT, Herzog RW, Anegon I, Adjali O. Measuring immune responses to recombinant AAV gene transfer. Methods Mol Biol. 2011 ;807 :259-72

10. Attig L, Larcher T, Gertler A, Abdennebi-Najar L, Djiane J (2011) Postnatal leptin is necessary for maturation of numerous organs in newborn rats. Organogenesis 7, 88-94.

11. Baril P, Touchefeu Y, Cany J, Cherel Y, Thorne S, Tran L, Conchon S, Vassaux G (2011) Differential biodistribution of oncolytic poxvirus administered systemically in an autochthonous model of hepatocellular carcinom. J. Gene Med.

12. Cherel Y (2011) Intérêt d’une biopsie musculaire chez le chien et le chat. Le nouveau praticien 9, 62-65.

13. Clouet J, Pot-Vaucel M, et al. (2011) Characterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression. Bmc Musculoskeletal Disorders, 12.

14. Daouk T, Larcher T, Rouspard F, Lyphout L, Rigaud C, Ledevin M, Loizeau V, Cousin X (2011) Long-term food-exposure of zebrafish to pcb mixtures mimicking some environmental situations induces ovary pathology and impairs reproduction ability. Aquat Toxicol 105, 270-278.

15. Dupas T, Rouaud T, Rouger K, Lieubeau B, Cario-Toumaniantz C, Fontaine-Perus J, Gardahaut MF, Auda-Boucher G (2011) Fetal muscle contains different CD34(+) cell subsets that distinctly differentiate into adipogenic, angiogenic and myogenic lineages. Stem Cell Research 7, 230-243.

16. Ellinwood NM, Ausseil J, et al. (2011) Safe, Efficient, and Reproducible Gene Therapy of the Brain in the Dog Models of Sanfilippo and Hurler Syndromes. Molecular Therapy 19, 251-259.

17. Esnault E, Bonsergent C, et al. (2011) A novel chicken lung epithelial cell line: Characterization and response to low pathogenicity avian influenza virus. Virus Research 159, 32-42.

18. Guevel L, Lavoie JR, Perez-Iratxeta C, Rouger K, Dubreil L, Feron M, Talon S, Brand M, Megeney LA (2011) Quantitative Proteomic Analysis of Dystrophic Dog Muscle. Journal of Proteome Research 10, 2465-2478.

19. Hoffmann T, Munier S, et al. (2011) Lenght variations in the NA stalk of an H7N1 inflluenza virus have opposite effects on viral excretion in chickens and ducks. J. Virol.

20. Hordeaux J, Deniaud J, Bemelmans I, Bertrand L, Moreau S, Amiaud J, Wyers M, Cherel Y, Colle MA (2011) Histopathologic Changes of the Ear in Canine Models of Mucopolysaccharidosis Types I and VII. Veterinary Pathology 48, 616-626.

21. Jean E, Laoudj-Chenivesse D, et al. (2011) Aldehyde dehydrogenase activity promotes survival of human muscle precursor cells. Journal of Cellular and Molecular Medicine 15, 119-133.

22. Joussemet B, Belbelaa B, et al. (2011) Neonatal systemic deliveray of scaav9 in rodents and large animals results in gene transfer to rpe cells in retina. Experimental Eye Research 93, 491-502.

23. Timsit E, Albaric O, Colle MA, Costiou P, Cesbron N, Bareille N, Assie S (2011) Clinical and Histopathologic Characterization of a Central and Peripheral Axonopathy in Rouge-des-pres (Maine Anjou) Calves. Journal of Veterinary Internal Medicine 25, 386-392.

24. Book: Methods in Molecular Biology 807, 2011 – Adeno-Associated Virus : Methods and Protocols – Richard O.Snyder, Philippe Moullier Editors.

25. Clark KR, Penaud-Budloo M. Evaluation of the fate of rAAV genomes following in vivo administration. Methods Mol Biol. 2011 ;807 :239-258.

26. Wang L, Blouin V, Brument N, Bello-Roufai M, Francois A. Production and purification of recombinant adeno-associated vectors. Methods Mol Biol. 2011 ;807 :361-404.

27. Cambien B, Richard-Fiardo P, Karimdjee BF, Martini V, Ferrua B, Pitard B, Schmid-Antomarchi H, Schmid-Alliana A. CCL5 neutralization restricts cancer growth and potentiates the targeting of PDGFRβ in colorectal carcinoma. PLoS One. (2011) 6:e28842.

28. Huin C, LeGall T, Barteau B, Pitard B, Montier T, Lehn T, Cheradame H and Guégan P. Evidence of DNA transfer across a model membrane by a neutral Amphiphilic block copolymer. J Gene Med (2011) 13:538-548

29. Richard-Fiardo P, Cambien B, Beilvert F, Pitard B, Schmid-Antomarchi H, Schmid-Alliana A. Effect of Fractalkine-Fc delivery in experimental lung metastasis using DNA /704 nanospheres. Cancer Gene Ther (2011) 18:761-772

30. David S, Carmoy N, Resnier P, Denis C, Misery L, Pitard B, Benoit JP, Passirani C, Montier T. In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model. (2012) Int J Pharm. 14, 423 (1): 108-15

31. Morille M, Passirani C, Dufort S, Bastiat G, Pitard B, Coll JL and Benoit JP. Tumor transfection after systemic injection of DNA lipid nanocpasules. Biomaterials. (2011) 32:2327-33

32. Le Bihan O, Chèvre R, Pitard B, and Lambert O. Probing the mechanism of action of cationic lipid/DNA lipoplxes at a nanometric scale. Nucleic Acids Res (2011), 39 1595-1609

33. Chèvre R, Le Bihan O, Beilvert F, Chatin B, Barteau B, Mével M, Lambert O, Pitard B. Amphiphilic Block Copolymers Enhance the Cellular Uptake of DNA Molecules through a Facilitated Plasma Membrane Transport. Nucleic Acids Res (2011), 39 1610-1622

34. Cany J, Barteau B, Tran L, Gauttier V, Archambeau O, Couty JP, Turlin B, Pitard B, Vasseaux G, Ferry N, Conchon S. AFP-specific immunotherapy Impairs Growth of Autochthonous Hepatocellular Carcinoma in Mice. J Hepatol (2011) 54, 115-121