Publications scientifiques 2012

1. Ni W, Le Guiner C, Moullier P, Snyder RO. Development and utility of an internal Threshold Control (ITC) Real-Time PCR Assay for Exogenous DNA Detection. PLoS One.2012 ;7(5) :e36461

2. Denard J, Beley C, Kotin R, Lai-Kuen R, Blot S, Leh H, Asokan A, Samulski RJ, Moullier P, Voit T, Garcia L, Svinartchouk F. Human galectin 3 binding protein interacts with recombinant adeno-associated virus type 6. J Virol.2012 Apr 11.

3. Nowrouzi A, Penaud-Budloo M, Kaeppel C, Appelt U, Le Guiner C, Moullier P, Kalle CV, Snyder RO, Schmidt M. Integration frequency and intermolecular recombination of rAAV vectors in non-human primate skeletal muscle and liver. Mol Ther.2012 Mar 27

4. Moullier P, Snyder RO. Recombinant adeno-associated viral vector reference standards. Methods Enzymol.2012 ;507 :297-311

5. Wakeling EN, Joussemet B, Costiou P, Fanuel D, Moullier P, Barkats M, Fyfe LC. Failure of lower motor neuron radial outgrowth precedes retrograde degeneration in a feline model of SMA. J Comp Neurol. 2012 Jun 1 ;520(8) :1737-1750

6. Book : Methods in Molecular Biology 807 – Adeno-Associated Virus – Methods and Protocols – Richard O.Snyder, Philippe Moullier Editors.

7. Petit L, Lhériteau E, Weber M, Le Meur G, Deschamps JY, Provost N, Mendes-Madeira A, Libeau L, Guihal C, Colle MA, Moullier P, Rolling F Restoration of vision in the PDE6B-deficient dog, a large animal model of Rod-cone dystrophy. Mol Ther.2012 Nov;20(11):2019-30

8. Angin M, Poirier N, Dilek N, Le Guiner C, Toromanoff A, Blancher A, Cherel Y, Deschamps JY, Tillou X, Renaudin K, Minault D, Hervouet J, Blancho G, Vanhove B, Anegon I, Le Mauff B. Gene transfer of human CD40Ig does not prevent rejection in a non-human primate kidney allotransplantation model. Transpl Immunol. 2012 Dec;27(4):139-45.

9. Beilvert F, Tissot A, Langelot M, Mevel M, Chatin B, Lair D, Magnan A, Pitard B. DNA/amphiphilic block copolymer nanospheres reduce asthmatic response in a mouse model of allergic asthma. Hum Gene Ther. (2012) 23: 597-608

10. Beilvert F, Mével , Châtin B, Pitard B. Local siRNA delivery by non viral vectors. Journal of Drug Delivery Science and Technology.(in press)

11. Billet L, Gomez JP, Brechet M, Jaffres PA, Le Gall T, Montier T, Bertrand E, Cheradame H, Guegan P, Mevel M, Pitard B, Benvengnu T, Lehn P, Pichon C, Midoux P. Gene Transfer by chemical vectors : comparative study of the endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line. Biomaterials. (2012) 33:2980-90.

12. David S., Montier T., Carmoy N., Clavreul A., Mével M., Pitard B., Benoit J.P., Passirani C., Treatment efficacy of DNA lipid nanocapsules and dna multimodular systems after systemic administration in a human glioma model. Journal of Gene Medecine. (2012) 14:769-775.

13. David S, Resnier P, Guillot A, Pitard B, Benoit JP, Passirani C. siRNA LNCs – A novel platform of lipid nanocapsules for systemic siRNA administration. Eur J Pharm Biopharm. (2012) 81:448-452

14. Arnaoty A, Pitard B, Bateau B, Bigot Y, Lecomte T. Novel approach for the development of new antibodies directed against transposase-derived proteins encoded by human neogenes. Methods Mol Biol. (2012) 859:293-305.

15. Mével M, Sainlos M, Chatin B, Oudrhiri N, Hauchecorne M, Lambert O, Vigneron JP, Lehn P, Pitard B, Lehn JM. Paromomycin and neomycin B derived cationic lipids: Synthesis and transfection studies. J Control Release. (2012) 158:461-469

16. Veron P, Leborgne C, Monteilhet V, Boutin S, Martin S, Moullier P, Masurier C. Humoral and Cellular capsid-specific immune responses to adeno-associated virus type 1 in randomized healthy donors. J Immunol.2012 Jun15 ;188(12) :6418-24

17. Deschamps JY, Gaulier JM, Podevin G, Cherel Y, Ferry N, Roux FA Fatal overdose after ingestion of a transdermal fentanyl patch in two non-human primates. Vet Anaesth Analg. 2012 Nov;39(6):653-6. doi: 10.1111/j.1467-2995.2012.00749.x. Epub 2012 Jul 13.

18. Desquesnes M, Ravel S, Deschamps JY, Polack B, Roux F. Atypical hyperpachymorph Trypanosoma (Nannomonas) congolense forest-type in a dog returning from Senegal. Parasite. 2012 Aug;19(3):239-47.
19. Le Guiner C, Moullier P, Arruda VR. Biodistribution and shedding of AAV vectors. Methods Mol Biol. 2011;807:339-59.

20. David S, Carmoy N, Resnier P, Denis C, Misery L, Pitard B, Benoit JP, Passirani C, Montier T. In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model. (2012) Int J Pharm. 14, 423 (1): 108-15