Human Gene Therapy journal cited the work of G. Gernoux et al. in a selection of “featured articles” from the latest issue (January 2015).
The study is the result of a fruitful collaboration between two teams from Atlantic Gene Therapies: Immunology of AAV-based gene transfer and ONIRIS/INRA 703 (APEX). The authors showed that an intramuscular administration of a AAV8 vector in the mouse leads to a rapid interaction of the viral vector with the host immune system and the transduction of immune key players : the dendritic cells.
The link of “featured articles” Human Gene Therapy :